This special session focuses on general aspects and special properties for agent-based modeling and simulations that allows them to be applied on several scientific domains, such as sociology, physics, chemistry, biology, ecology, and economy. The session is intended to bring together researchers and practitioners, so they can present the current status of their work and discuss the challenges they face in developing solutions and applications for agent-based simulations. Consequently, the design of these simulations aims not only to social contexts but also to more technical domains, which involves highly complex interactive systems.