The DCABES is a community working in the area of Distributed Computing and Applications in Business, Engineering, and Sciences, and is responsible for organizing meetings and symposia related to the field. (See previous meetings from the web site DCABES.) DCABES intends to bring together researchers and developers in the academic field and industry from around the world to share their research experience and to explore research collaboration in the areas of distributed parallel processing and applications. The 15th International Symposium on Distributed Computing and Applications to Business, Engineering and Science (DCABES 2016) will be held on August 24-26, 2016 in Paris, France. All papers accepted by DCABES Proceedings have been peer reviewed by more than two experts and carefully modified. Since DCABES 2010, Proceedings of the DCABES has been published by the IEEE Conference Publishing Services (CPS), and be sent to the EI and CPCI (ISTP) for index by the CPS. The EI and CPCI (ISTP) have regularly indexed proceedings of the DCABES. Distinguished papers, after further revisions, will be considered for possible publication in several SCI & EI indexed special issues of prestigious international journals.