For more than a decade, Graphene first and 2D materials immediately after, are animating the scientific landscape in several and manifold sectors. Today, it looks apparent that the main challenge laying ahead is the underlying technology, which has to deal with the inherent complexity of manufacturing. At the nanooscale in fact, the intrinsic crystal purity of the materials, and especially the control and engineering of the interfaces, be it with metals or with dielectrics, becomes paramount and dominates the device behavior. Hence the scope of this event, which gathers among the most active and brilliant research scientists in the field is to review the crucial limitations and discuss possible solutions (how to model, how to measure and especially how to fabricate). As result, this workshop is expected to draw some relevant conclusion on the present state of the art and propose some strategic visions toward future practical exploitation of these materials in RF electronics.