As it happens with design automation, Analog and Mixed-Signal test solutions are much less generic than their siblings from the digital world. In spite of the high costs associated to specification-based test, the industry seemed reluctant to invest in alternatives. Why would we change something that worked? But with the rise of safety-critical applications, reliability requirements are increasing and quality is nowadays a strong asset in competitive markets. Specification-based test cannot be considered perfect any longer. The golden reference is shattered and this is an opportunity for the Analog and Mixed-Signal test community.