Based on the complex network theory, this paper constructs the regional industry network by using the 2009-2014 corporate transfer data between enterprises of a bank in Yiwu, explores its topology structure,and analyzes the industrial structure change through the construction of homogeneous and heterogeneous networks. The result shows that: (1) 2012 as the boundary, the integral characteristic of industry network in Yiwu has periodic change. (2) Most of industries in Yiwu break through the relation pattern and develop new contact on the basis of original relationship so that the key basic industries be diversified gradually. (3) Wholesaling and manufacturing are the most important industries in local economy.