Whether the current specifications about ship collision force or standard formula proposed by researchers,in addition to the European Specifications which stiffness is constant,just considered the ship weight, impact velocity, which seldom considering the influence of stiffness of the structure. In this study, the influence of the maximum ship collision force of the single pile foundation was analyzed from the aspects of ship weight, the impact velocity, the shear modulus of the pile, the length of the pile foundation, the diameter of the pile and the upper load. We proposed the calculation formula of maximum ship collision force considering multi factor variable, and compared with the existing specifications. The results showed that the calculation results of the maximum ship collision force proposed by this research were close to the results of the European Specifications (K=5).