To investigate the proposed new approach for suppressing the vibration of structures. The experimental system consists of a clamped-free rectangular plate, a LQR controller and a magnetostrictive actuator utilized for suppressing the vibrations induced by external excitation. Interaction between structure and actuator was considered, and the interaction model was incorporated in the control system. Vibration reduction strategy has been performed resorting to the actuator in optimal position to suppress the specified modes using LQR (linear quadratic regulator) based on modal control switching. The experimental results demonstrate the effectiveness of the proposed methodology. Considering Structure-actuator interaction (SAI) is a key procedure in controller design especially for flexible structures.