A study of the mechanisms of childhood trauma influencing reward processing in individuals with suicidal ideation
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报告开始:2025年01月10日 19:40(Asia/Shanghai)

报告时间:10min

所在会场:[P3] 研究生分论坛三 [P3] 研究生分论坛三

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摘要
Objective
    Childhood trauma(CT), as an early negative stressor, is a distal risk factor for suicidal behaviour. However, not all suicidal ideators have experienced early life trauma. Studies have found that individuals with suicidal ideation exhibit abnormalities in their reward processing mechanisms, and childhood trauma may be a key modulating factor that alters the neural mechanisms of reward processing in individuals with suicidal ideation. To test this hypothesis, we will compare the behavioral performance and brain mechanisms of reward processing between individuals with suicidal ideation who have experienced childhood trauma and those who have not.
Methods 
    This study comprises four groups of participants, with approximately 30 individuals in each group, all recruited through advertisements at Tianjin University. The Chinese version of the Childhood Trauma Questionnaire (CTQ) is utilized to assess the history of childhood trauma, and the Chinese version of the Beck Scale for Suicide Ideation (BSI-CV) is employed to differentiate between individuals with and without lifetime suicidal ideation. The four groups of participants included: those with childhood trauma and suicidal ideation (CT+SI, n = 30), those with suicidal ideation but without childhood trauma (only SI, n = 30), those with childhood trauma but without suicidal ideation (only CT), and healthy controls (n = 30). These participants underwent ERP while performing both the monetary incentive delay task and the social incentive delay task.
Results & Discussion
    Expected experimental results: The main effects of childhood trauma and suicidal ideation are significant in terms of behavioral performance (hit rate and reaction time) in monetary and social incentive delay tasks, as well as in the levels of electroencephalographic indicators (Cue-P3, SPN, CNV, RewP, Feedback-P3), and their interaction effect is also significant.
    Childhood trauma moderates the impact of suicidal ideation on reward processing in young adults, including the efficiency of processing reward stimuli and the anticipation and consumption of rewards.
关键词
Childhood trauma,reward processing,suicidal ideation,ERP
报告人
王宏硕
学生 天津大学

稿件作者
王宏硕 天津大学
安莉 天津大学
艾卉 天津大学
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重要日期
  • 会议日期

    01月10日

    2025

    01月11日

    2025

  • 01月08日 2025

    初稿截稿日期

  • 01月14日 2025

    注册截止日期

  • 01月17日 2025

    报告提交截止日期

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