Objective
Childhood trauma(CT), as an early negative stressor, is a distal risk factor for suicidal behaviour. However, not all suicidal ideators have experienced early life trauma. Studies have found that individuals with suicidal ideation exhibit abnormalities in their reward processing mechanisms, and childhood trauma may be a key modulating factor that alters the neural mechanisms of reward processing in individuals with suicidal ideation. To test this hypothesis, we will compare the behavioral performance and brain mechanisms of reward processing between individuals with suicidal ideation who have experienced childhood trauma and those who have not.
Methods
This study comprises four groups of participants, with approximately 30 individuals in each group, all recruited through advertisements at Tianjin University. The Chinese version of the Childhood Trauma Questionnaire (CTQ) is utilized to assess the history of childhood trauma, and the Chinese version of the Beck Scale for Suicide Ideation (BSI-CV) is employed to differentiate between individuals with and without lifetime suicidal ideation. The four groups of participants included: those with childhood trauma and suicidal ideation (CT+SI, n = 30), those with suicidal ideation but without childhood trauma (only SI, n = 30), those with childhood trauma but without suicidal ideation (only CT), and healthy controls (n = 30). These participants underwent ERP while performing both the monetary incentive delay task and the social incentive delay task.
Results & Discussion
Expected experimental results: The main effects of childhood trauma and suicidal ideation are significant in terms of behavioral performance (hit rate and reaction time) in monetary and social incentive delay tasks, as well as in the levels of electroencephalographic indicators (Cue-P3, SPN, CNV, RewP, Feedback-P3), and their interaction effect is also significant.
Childhood trauma moderates the impact of suicidal ideation on reward processing in young adults, including the efficiency of processing reward stimuli and the anticipation and consumption of rewards.
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