The use of seawater and LC3 cement has been gaining attention in recent years as a potential solution to address the environmental impact of conventional cement production. LC3 stands for Limestone Calcined Clay Cement, a type of cement made by blending calcined clay and limestone. One of the benefits of using LC3 cement is that it has a lower carbon footprint than traditional Portland cement due to its reduced reliance on clinker, which is a major contributor to carbon dioxide emissions in cement production. Additionally, the use of seawater as a mixing water for LC3 cement has shown promising results in reducing the amount of freshwater consumption and improving the durability of the concrete. This study, therefore, focuses on the performance of LC3 cement with seawater in comparison to common/fresh water. It was observed that seawater has shown a positive performance on the hydration behavior, pozzolanic reaction degree as well as on compressive strength of LC3 cement. This innovative approach has the potential to not only reduce the environmental impact of cement production with the use of low-clinker cement such as LC3 alongside provide a sustainable solution by reducing the demand for freshwater consumption in the construction industry.