254 / 2024-09-02 15:41:59

Study on Evaluation of Lower Extremity Arterial Disease by Photoacoustic Tomography

Photoacoustic tomography,blood oxygen calculate,lower extremity imaging

As an important sign of inflammatory diseases, tissue hypoxia has been gradually paid attention to and used in the diagnosis of various peripheral vascular and metabolic diseases, and how to provide accurate blood oxygen information of deep tissues has become the key. Photoacoustic tomography (PACT) is a good solution to this problem. Due to its unique mechanism of light absorption differences in biological tissues, PACT is inherently sensitive to the functional and molecular information of biological tissues. There have been studies using photoacoustic tomography for arthritis, but its transducer adopts the commonly used ultrasonic linear array, which can not fit the shape of human lower limbs. We use our self-developed photoacoustic computational tomography system to provide super resolution and large depth photoacoustic images while providing ultrasound images within the target area. And through the effective extraction of photoacoustic spectral features and the use of spectral features deconmixation algorithm, the blood oxygen saturation is calculated, so that the photoacoustic imaging can show more. Through the above studies, new structural and functional imaging and new methods and tools for the diagnosis of various human peripheral vascular and metabolic diseases are provided.