摘要详情
229 / 2024-07-30 08:42:37
Metalens for miniatured two-photon microscopy
Metalens, miniatured two-photon microscopy, geometric phase
全文待审
The miniatured two-photon microscope is promising for monitoring brain activities of free-behaving animals or in-situ endoscope diagnosis. Ultrathin and lightweight metalens presents a potential alternative to bulky refractive lenses for a miniaturized optical system. However, designing and fabricating achromatic metalens covering the near-infrared and visible light spectrum range is challenging. We proposes and demonstrates a metalens focusing at one wavelength while capable of multichannel two-photon microscopy due to the nonlinear properties of two-photon excitation. The metalens was designed solely to focus near-infrared excitation laser using geometric phase regardless of the chromatic correction for visible emission light. Our method simplifies the design process, reduces manufacturing costs, and increases the focusing efficiency for the excitation light while maintaining a high transmittance for visible light. Using the metalens, two-photon biological imaging with three different labels was experimentally demonstrated with subcellular resolution.
The miniatured two-photon microscope is promising for monitoring brain activities of free-behaving animals or in-situ endoscope diagnosis. Ultrathin and lightweight metalens presents a potential alternative to bulky refractive lenses for a miniaturized optical system. However, designing and fabricating achromatic metalens covering the near-infrared and visible light spectrum range is challenging. We proposes and demonstrates a metalens focusing at one wavelength while capable of multichannel two-photon microscopy due to the nonlinear properties of two-photon excitation. The metalens was designed solely to focus near-infrared excitation laser using geometric phase regardless of the chromatic correction for visible emission light. Our method simplifies the design process, reduces manufacturing costs, and increases the focusing efficiency for the excitation light while maintaining a high transmittance for visible light. Using the metalens, two-photon biological imaging with three different labels was experimentally demonstrated with subcellular resolution.
The miniatured two-photon microscope is promising for monitoring brain activities of free-behaving animals or in-situ endoscope diagnosis. Ultrathin and lightweight metalens presents a potential alternative to bulky refractive lenses for a miniaturized optical system. However, designing and fabricating achromatic metalens covering the near-infrared and visible light spectrum range is challenging. We proposes and demonstrates a metalens focusing at one wavelength while capable of multichannel two-photon microscopy due to the nonlinear properties of two-photon excitation. The metalens was designed solely to focus near-infrared excitation laser using geometric phase regardless of the chromatic correction for visible emission light. Our method simplifies the design process, reduces manufacturing costs, and increases the focusing efficiency for the excitation light while maintaining a high transmittance for visible light. Using the metalens, two-photon biological imaging with three different labels was experimentally demonstrated with subcellular resolution.
重要日期
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会议日期
09月08日
2024
至09月12日
2024
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09月15日 2024
初稿截稿日期
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09月15日 2024
注册截止日期
主办单位
ShenZhen University
联系方式
- Organizing Committee
- ic******@163.com
- +86********
历届会议
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2009年05月11日 中国 哈尔滨市
2009年纳米光子学国际会议
