摘要详情

ID / 提交时间

131 / 2023-10-18 14:12:57

标题

Diarylphosphine oxide-involved radical reactions

关键字

Diarylphosphine Oxide,Radical Reaction,Phosphorylated Aromatics

主题及专题

全体主题

状态

摘要待审

作者

Xiaolan Chen / Zhengzhou University

摘要

Phosphorylated aromatics, a class of organic compounds, have wide-ranging applications in organic synthesis, medicinal chemistry, and materials science.^[1]Utilizing phosphorus radical-mediated approaches, researchers can readily access various structurally diverse phosphorus-containing scaffolds in a rapid and straightforward manner.^[2] Our research primarily centers on designing and developing an innovative protocol that is both environmentally friendly and efficient for synthesizing phosphorylated aromatics. Moreover, a wide range of phosphorylated aromatics including phenanthridines, quinolines, and benzothiazoles were successfully synthesized via a visible-light-induced proton-coupled electron transfer strategy. The reaction mechanism, structure-reactivity relationship, and substrate scope will be discussed in detail.