738 / 2019-05-13 23:00:45
Identification of transcription factors that regulate autophagy during environmental stress
autophagy,TGA9,ATG8
摘要录用
Diane Bassham / Iowa State University
Autophagy is a macromolecule degradation pathway in which cellular components are transported to the vacuole to recycle nutrients during nutrient deficiency and senescence and to clear damaged molecules and organelles during environmental stress. Autophagy therefore contributes to plant survival and growth during adverse environmental conditions. Autophagy can be non-selective, indiscriminately degrading cellular components, or selective, in which substrates for autophagy are recognized by receptor proteins and targeted for degradation. Autophagy is active at a low level under normal conditions for homeostasis and is upregulated by many different stresses. We are analyzing the function and regulation of autophagy under different abiotic stress conditions. Upstream regulators of autophagy activation have been identified, some of which are common to multiple stresses and some are specific to individual stresses. Recently we have identified a set of transcription factors that regulate the expression of autophagy-related genes and are examining their role in activating autophagy in response to environmental cues.
重要日期
  • 会议日期

    06月16日

    2019

    06月21日

    2019

  • 05月01日 2019

    初稿截稿日期

  • 06月21日 2019

    注册截止日期

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